Fig. 9.

Inactivation of polyubiquitin significantly attenuates the virulence of C. albicans in a mouse model of systemic candidiasis.A. Kidney burdens measured at 72 h post infection (means and standard deviations for six animals): UBI4/UBI4, MLC125, white bar; ubi4/ubi4, MLC60, black bar; ubi4/ubi4/UBI4, MLC61, grey bar (Table 1).B. Infection outcome scores calculated after 3 days (means and standard deviations for six animals), where higher outcome scores reflect more severe infection.In both panels, **P < 0.01.