Table 2.

Association of Porphyromonas gingivalis with arthritis in in vitro studies

Focus	Assay	Associated bacteria	Sample	Reference
Protein citrullination by P. gingivalis and breaking tolerance in RA	Immunoblotting Mass spectrometry	Porphyromonas gingivalis	Cell culture	Wegner et al. (46)
P gingivalis infection and its effects on cell cycle progression and apoptosis of human articular chondrocytes	Scanning electron microscopy Double immunofluorescence Cytometry TUNEL Western blot analysis	Porphyromonas gingivalis	Cell culture	Pischon et al. (52)
Exacerbation of action of a proapoptotic fibronectin on nitric oxide by bacteria	Western blot analysis Immunofluorescence. ELISA	Porphyromonas gingivalisStreptococcus mutans	Cell culture	Ghosh et al., 2008. (53)
Hyperinflammatory genotype and functional interferences in innate and adaptive immune responses	ELISA	Porphyromonas gingivalisAggregatibacter actinomycetemcomitans	Mice	Trombone et al. (31)