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. Author manuscript; available in PMC: 2011 Apr 29.
Published in final edited form as: Oncogene. 2009 Feb 9;28(12):1485–1495. doi: 10.1038/onc.2008.459

Figure 1.

Figure 1

Mek1 deletion fails to alter oncogenic Ras-induced epidermal hyperplasia. Histology and immunofluorescence staining of adult mouse skin after 5 days of treatment with ethanol (vehicle) or 4-hydroxytamoxifen (4OHT). Tissue genotypes and treatment groups are noted at the top of each column. Skin sections were stained with antibodies against keratin 6, loricrin, keratin 10, keratin 5, Ki67, and β4 integrin (orange), and counterstained with Hoechst 33342 nuclear dye (blue) as noted at the right of each corresponding row; scale bars = 50 μm.