Figure 2.
Detection of implantation sites in wild type, Lpar1(−/−)Lpar2(−/−), Lpar3(−/−), and S1pr2(−/−)S1pr3(−/−) females on gestation day 4.5 by Evans blue dye injection. A. Uterine images. Red arrows indicate implantation sites. No implantation sites were detected in the Lpar3(−/−) uterus but healthy-looking blastocysts were flushed from the uterine horns (data not shown). B. Number of implantation sites. N=5–9. Error bars represent standard deviation.