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. 2011 Apr 29;6(4):e18490. doi: 10.1371/journal.pone.0018490

Table 6. The effect of intravenous administration with vehicle or honokiol on hematology of rats and data represented the mean ± SD (n = 5).

Parameter Vehicle Honokiol(20 mg/kg) Honokiol(40 mg/kg) Honokiol(80 mg/kg)
WBC (109/L) 3.64±0.71 3.56±0.78 4.03±1.11 3.73±1.21
NEU (109/L) 0.299±0.118 0.342±0.213 0.356±0.181 0.371±0.180
LYM (109/L) 3.32±0.61 3.11±0.86 3.55±1.02 3.43±1.03
MONO (109/L) 0.042±0.023 0.039±0.023 0.046±0.031 0.048±0.029
EOS (109/L) 0.032±0.011 0.031±0.015 0.034±0.015 0.029±0.011
BASO (109/L) 0.003±0.004 0.003±0.001 0.005±0.006 0.005±0.003
NEU% (%) 8.72±1.98 10.01±4.31 9.89±3.92 9.91±3.92
LYM% (%) 90.1±2.7 88.6±5.7 88.5±5.6 88.9±5.2
MONO% (%) 1.358±0.586 1.137±0.962 1.801±1.972 1.153±0.881
EOS% (%) 0.841±0.139 0.851±0.314 0.871±0.367 0.724±0.286
BASO% (%) 0.120±0.075 0.095±0.085 0.153±0.089 0.127±0.080
RBC (1012/L) 6.36±0.39 6.61±0.38 6.41±0.29 6.28±0.22
HGB (g/L) 138±9 131±8 135±6 128±8
HCT (%) 41.2±1.3 41.3±1.4 41.2±1.5 40.9±1.3
MCV (fL) 64.6±1.9 64.1±2.1 64.0±1.8 64.2±1.6
MCH (pg) 20.8±0.8 20.8±0.7 20.5±0.6 20.7±0.7
MCHC (g/L) 324±5 322±6 321±8 320±7
RET (%) 3.56±0.91 3.63±0.87 3.43±0.92 3.49±0.69
PLT (109/L) 1134±123 1143±98 1161±126 1150±172
PT (sec) 8.2±0.4 8.1±0.5 8.2±0.2 8.2±0.2
APTT (sec) 17.2±1.5 17.3±1.9 17.2±1.5 17.1±1.6