Figure 3. Myometrial 
model.
Properties of 
are derived primarily from experimental data of Serrano et al., [43] and Hering et al., [44]. A, V-dependent steady-states of activation (
) and inactivation (
); experimental data in brackets were extrapolated from the published I–V relationships and normalized to the maximum value. B, superimposed simulated and experimental time-to-peak of 
at different V stepped from 
of 
; a function for the V-dependent activation time constant is chosen so that the simulated time-to-peak (empty circles) matched the experimental data (solid circle). C, V-dependent inactivation time constant (
). D, simulated 
at voltage steps of 
to 
from a 
of 
; E, simulated peak I–V relationship of 
and experimental I–V data. In both D and E, all data are normalized to the peak current value at 
.