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. 2011 Apr 29;6(4):e18081. doi: 10.1371/journal.pone.0018081

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Sandersius et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(a) An example of cell morphology of a cell sheet grown in two dimensions using the ScEM with 128 to 256 elements per cell. Cells are colored randomly in order to distinguish cells. (b) The scaled intercellular interaction potential between elements. Beyond the equilibrium distance there are decaying interactions between elements. This region is outlined with a color gradient. (c) High magnification of elements of several neighboring cells. Cells are distinguished by different colors. Demonstrated here are the different cut-off ranges for which two elements from different cells are considered to be interacting strongly enough that their associated cells are neighbors. The cut-off range is , and is the diameter of an element and/or the equilibrium distance of the interaction potential shown in (b).

Inline graphic — (a) An example of cell morphology of a cell sheet grown in two dimensions using the ScEM with 128 to 256 elements per cell. Cells are colored randomly in order to distinguish cells. (b) The scaled intercellular interaction potential between elements. Beyond the equilibrium distance there are decaying interactions between elements. This region is outlined with a color gradient. (c) High magnification of elements of several neighboring cells. Cells are distinguished by different colors. Demonstrated here are the different cut-off ranges for which two elements from different cells are considered to be interacting strongly enough that their associated cells are neighbors. The cut-off range is , and is the diameter of an element and/or the equilibrium distance of the interaction potential shown in (b).