Table 1. Summary of experimental design.
| Experimental Design for data in Figure #2 | |||
| Treatment Cohorts (n) | Cardiac Allograft1 | CSA Drug Therapy (Total Days)2 | ImmunotherapyTh2.R (Day administered)3 |
| 1. n = 3 (Rejection Control) | Y | N | N |
| 2. n = 3 (Treatment Control) | Y | Y (28) | N |
| 3. n = 3 (Sub-optimal Drug Therapy) | Y | Y (18) | N |
| 4. n = 3 (Immunotherapy) | Y | N | Y (0) |
| 5. n = 3 (Immunotherapy) | Y | Y (18) | Y (0) |
1
Y = yes, N = no; DA donor hearts transplanted into BN recipient rats.
2
Cyclosporine (CSA) administered subcutaneously (10 mg/kg/day).
3
Th2.R = Th2 cells were generated from host BN CD4+ T cells.
4
Rapamycin (Rapa) administered i.p (1.5 mg/kg/day); CMC = carboxymethylcellulose.