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. 2011 Apr 29;6(4):e18783. doi: 10.1371/journal.pone.0018783

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Saulnier et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Metabolic reactions present in both strains are highlighted in dark grey. Metabolic reactions only present in L. reuteri ATCC 55730 are highlighted in black. Abbreviations are indicated for reactions present at least in one strain. [e]: extracellular; 6pgg: 6-phospho-beta-D-glucosyl-(1,4)-D-glucose; acgal6p: N-acetylgalactosamine 6-phosphate; acgala: N-Acetyl-D-galactosamine; ACGALpts: N-acetylgalactosamine PTS; a-gal-D: alpha-D galactose; CELBpts: cellobiose transport via PEP:Pyr PTS; cellb: cellobiose; CPS_LPL2: capsular polysaccharide linkage unit, LPL specific; CPSS_LPL2: CPS synthase complex, LPL specific; dtdp6dm: dTDP-6-deoxy-L-mannose; dtdpddg: dTDP-4-dehydro-6-deoxy-D-glucose; dtdpddm: dTDP-4-dehydro-6-deoxy-L-mannose; dtdpglc: dTDPglucose; dttp: dTTP; f6p: D-Fructose 6-phosphate; fru: D-Fructose; FRUK: fructokinase; g1p: D-Glucose 1-phosphate; G1PTMT: glucose-1-phosphate thymidylyltransferase; g6p: D-glucose 6-phosphate; g6p-B: beta-D-glucose 6-phosphate; G6P: Glucose-6-phosphate isomerase; gal: D-galactose; gal1p: alpha-D-Galactose 1-phosphate: GALK2: galactokinase; GALM: aldose 1-epimerase; GALS3: a-galactosidase (melibiose); GALSZ: beta-galactosidase; GALT: galactose-1-phosphate uridylyltransferase; GALU: UTP-glucose-1-phosphate uridylyltransferase; glc-D: D-glucose; lcts: lactose; LCTSt6: lactose transport in/out via proton symport; MALP: maltose phosphorylase; malt: maltose; MALT: alpha-glucosidase; man: D-mannose; man1p: D-mannose 1-phosphate; man6p: D-mannose 6-phosphate; MAN6PI: mannose-6-phosphate isomerase; MANpts: D-mannose transport via PEP:Pyr PTS; melib: melibiose; PGGH: 6-phospho-beta-glucosidase; PGI: glucose-6-phosphate isomerase; PGMT: phosphoglucomutase; PGMT_B: b-phosphoglucomutase; PMANM: phosphomannomutase; raffin: raffinose; RAFGH; raffinose galactohydrolase; suc6p: sucrose 6-phosphate: SUCpts: sucrose transport via PEP:Pyr PTS; sucr: sucrose; TDPDRE: dTDP-4-dehydrorhamnose 3,5-epimerase; TDPDRR: dTDP-4-dehydrorhamnose reductase; TDPGDH: dTDPglucose 4,6-dehydratase; tre: trehalose; tre6p: alpha'-trehalose 6-phosphate; TREpts: trehalose transport via PEP:Pyr PTS; udpg; UDPglucose; UDPG4E: UDPglucose 4-epimerase; udpgal: UDPgalactose. The red boxes depict compound that can be incorporated in biomass.