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. 2011 Apr 29;6(4):e18783. doi: 10.1371/journal.pone.0018783

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Saulnier et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Genes encoding similar functions in EPS biosynthesis have a similar color. Genes indicated in dark blue encode proteins putatively involved in the regulation of EPS production and polymerization. Genes indicated in white encode putative glycosyltransferases. Genes indicated in light blue encode proteins involved in the biosynthesis of the dTDP-rhamnose precursor. Genes indicated in plain blue encode hypothetical proteins. Genes indicated in dark grey encode the putative polysaccharide transporter and polymerase. Transposases are indicated by a triangle. Intergenic regions are not represented at this scale. cpsA: cell envelope related transcriptional regulator; cps1C: polysaccharide biosynthesis protein; GFT: galactofuranosyltransferase; GT: glycosyltransferase; HEP: hypothetical extracellular protein; HP: hypothetical protein; P: permease; PS: polysaccharide synthesis protein; recX: regulatory protein; rfbA: glucose-1-phosphate thymidylyltransferase; rfbB: dTDP-glucose 4,6-dehydratase; rfbC: dTDP-4-dehydrorhamnose 3,5-epimerase; rfbD: dTDP-4-dehydrorhamnose reductase; rfbF: dTDP-rhamnosyl transferase; rfbP: undecaprenyl-phosphate galactose phosphotransferase; rgbP: group 2 glycosyl transferase; rmLA1, rmLA2: glucose-1-phosphate thymidyl transferase; rmLB: dTDP glucose 4,6-dehydratase; rmLD: dTDP-4-dehydrorhamnose reductase; welE: priming glycosyltransferase; welF, welG: glycosyltransferase; welH: α-L-rhamnose α-1,3-L-rhamnosyltransferase; welI, welJ: glycosyltransferase; wzx: flippase; wzx; non-specific protein-tyrosine kinase; wzx: polysaccharide transporter; wzy: polymerase.