Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Apr 29;6(4):e18783. doi: 10.1371/journal.pone.0018783

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Saulnier et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

The thiamine synthesis pathway is predicted to be complete in strain 55730 only. Metabolic reactions present in both strains 55730 and 6475 are highlighted in dark grey. Metabolic reactions present only in L. reuteri ATCC 55730 are highlighted in black. 2mahmp: 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate; 4ahmmp: 4-amino-5-hydroxymethyl-2-methylpyrimidine; 4ampm: 4-amino-2-methyl-5-phosphomethylpyrimidine; 4mhetz: 4-methyl-5-(2-hydroxyethyl)-thiazole; 4mpetz: 4-methyl-5-(2-phosphoethyl)-thiazole; AHMMPS: 4-amino-5-hydroxymethyl-2-methylpyrimidine synthetase; air: 5-amino-1-(5-phospho-D-ribosyl)imidazole; DXPS: 1-deoxy-D-xylulose 5-phosphate synthase; dxyl5p: 1-deoxy-D-xylulose 5-phosphate; g3p: glyceraldehyde 3-phosphate; gcald: glycolaldehyde; gly: glycine; HETZK: hydroxyethylthiazole kinase; HMPK1: hydroxymethylpyrimidine kinase (ATP); MCOOH: MPT synthase small subunit MoaD; MCOSH: MPT synthase sulfurylated small subunit (MoaD-SH); MOADCST: MoaD:cysteine sulfur transferase; PMPK: phosphomethylpyrimidine kinase; pyr; pyruvate; thm: thiamine; thm[e]: thiamine (extracellular); THMabc: thiamine transport via ABC system; thmmp: thiamine monophosphate; thmpp: thiamine diphosphate; THZPSN2: thiazole phosphate synthesis; TMDPK: thiamine diphosphokinase; TMPKr: thiamine-phosphate kinase; TMPPP: thiamine-phosphate diphosphorylase. The red boxes depict compound that can be incorporated in biomass.