Skip to main content
. 2011 Apr 29;6(4):e18974. doi: 10.1371/journal.pone.0018974

Figure 3. Daily locomotor activities under LD cycles reveal genetic interactions between PDF and CRY signaling pathways.

Figure 3

Averaged activity of various genotype flies for a six-day-period under 8∶16 LD (A–D), 12∶12 LD (E–H), and 16∶8 LD (I–L) entrainment conditions. (A, E, I) w1118 control flies; (B, F, J) pdfr5304 single mutant flies; (C, G, K) pdfr5304; ; cryb/01 double mutant flies; (D, H, L) cry-G4(19); cryb ss Pdf01 double mutant flies. Both double mutant flies display lack of anticipatory peaks under LD cycles. Note that, in pdfr single mutants, the longer the day length becomes the more pronounced the advanced evening phenotype. For the experiment shown, the numbers of animals averaged are 32 (A), 31 (B), 32 (C), 32 (D), 30 (E), 14 (F), 15 (G), 32 (H), 32 (I), 31 (J), 31 (K), and 32 (L).