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. 2011 Apr 29;6(4):e19176. doi: 10.1371/journal.pone.0019176

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Bhat et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Deep sequencing revealed HERV-W and related -env, -LTR and -pol RNA tags in fetal and adult samples, although the frequency of env tags was highest in all specimens. (B) Transcript levels of HERV-W env gene normalized to GAPDH, were highest in fetal brain samples. (C) Western blot analysis disclosed up-regulation of Syncytin-1 immunoreactivity in fetal samples relative to β-actin expression.