Table 2. Echocardiography of 20-day Twist1 TG mice.
WT (n = 6) | Twist1DD (n = 7) | |
IVS; d (mm) | 0.59±0.02 | 0.72±0.03 |
LVID; d (mm) | 2.68±0.04 | 2.72±0.07 |
LVPW; d (mm) | 0.61±0.01 | 0.71±0.05 |
IVS; s (mm) | 0.69±0.03 | 0.72±0.03 |
LVID; s (mm) | 1.61±0.03 | 2.24±0.07* |
LVPW; s (mm) | 0.87±0.02 | 0.76±0.05 |
LV Vol; d (ìl) | 26.84±0.91 | 28.57±1.50 |
LV Vol; s (ìl) | 7.49±0.42 | 18.21±1.07** |
EF % | 72.02±1.25 | 38.43±2.11** |
FS % | 39.96±1.04 | 18.20±1.20** |
LV Mass (mg) | 41.31±0.72 | 54.98±3.46 |
LVMass Corrected (mg) | 33.05±0.57 | 43.98±2.77 |
*P<0.05 and
**P<0.005.
Abbreviations: IVS, interventricular septum; LVID, left ventricular internal; LVPW, left ventricular posterior wall; LV Vol, left ventricular volume; EF, ejection fraction; FS, fractional shortening; d, diastolic; s, systolic.