Table 2. Infection and blockage of fleas by Y. pestis strains.
Strain | Y. pestis CFU/fleaa at: | Fleas infected at 28 days | Blockage rate | Fleas(n) | |
0 day | 28 days | ||||
KIM6+ wild type | 8.2×104±5.5×1041.8×105±1.3×105 | 4.8×105±2.4×1056.0×105±3.4×105 | 100%65% | 38%45% | 106113 |
KIM6+ ΔhmsT | 5.1×104±2.8×1049.2×104±4.9×104 | 3.1×105±1.3×1056.3×105±3.3×105 | 90%80% | 20%16% | 106119 |
KIM6+ ΔhmsT (p-hmsT) | 1.0×105±7.7×1041.2×105±1.4×105 | 7.7×105±4.5×1055.8×105±4.2×105 | 95%90% | 46%31% | 10590 |
KIM6+ Δy3730 | 5.8×104±7.3×1044.6×104±4.1×104 | 2.9×105±3.1×1053.2×105±3.4×105 | 70%70% | 1%5% | 88108 |
KIM6+ Δy3730 (p-y3730) | 4.2×104±4.0×1041.5×105±0.8×105 | 6.4×105±3.7×1057.2×105±2.4×105 | 50%100% | 37%47% | 106106 |
KIM6+ Δy3730 (p-M-y3730) | 3.3×105±2.2×1054.6×104±2.0×104 | 4.4×105±3.2×1054.3×105±2.7×105 | 95%95% | 8%6% | 108107 |
KIM6+ Δy3730 (p-hmsT) | 2.7×105±1.8×1051.5×105±0.8×105 | 8.8×105±2.2×1058.5×105±3.0×105 | 95%90% | 42%36% | 101110 |
KIM6+ ΔhmsTΔy3730 | 1.6×105±1.5×1052.0×104±1.9×104 | 2.7×105±3.9×1053.6×104±4.4×104 | 90%24% | 0%2% | 107109 |
KIM6+ ΔhmsTΔy3730 (p-y3730) | 6.2×104±5.9×1041.7×104±1.2×104 | 5.0×105±3.6×1055.4×105±3.0×105 | 70%85% | 24%33% | 108111 |
The results of two experiments with each bacterial strain are shown.
Mean±SD.