Table 2. Clinical characteristics of hospitalized TB patients in the 309 Hospital.
Characteristics | Total | Patients with non-MDR -TB | Patients with MDR-TB excluding XDR-TB | Patients with XDR-TB | P |
n = 3270(%) | n = 2694 (%) | n = 528 (%) | n = 48 (%) | ||
Sites of TB | 0.013 | ||||
Extrapulmonary TB | 256 (7.8) | 228 (8.5) | 25 (4.7) | 3 (6.2) | |
Pulmonary TB | 3014 (92.2) | 2466 (91.5) | 503 (95.3) | 45 (93.8) | |
Lower lung field TB (n = 3024) | 1575 (52.1) | 1286 (52.0) | 262 (52.0) | 27 (60.0) | 0.563 |
TB history | <0.001 | ||||
New | 1392 (42.6) | 1211 (45.0) | 166 (31.4) | 15 (31.2) | |
Retreatment | 1878 (57.4) | 1483 (55.0) | 362 (68.6) | 33 (68.8) | |
Smear-positivity at treatment onset (n = 2674) | 1951 (73.0) | 1526 (70.9) | 392 (82.2) | 33 (75.0) | <0.001 |
Radiological findings at onset | 0.545 | ||||
Non-cavitary | 1492 (45.6) | 1239 (46.0) | 234 (44.3) | 19 (39.6) | |
Cavitary disease | 1778 (54.4) | 1455 (54.0) | 294 (55.7) | 29 (60.4) | |
Family history of TB, yes (n = 3205) | 133 (4.1) | 100 (3.8) | 31(6.2) | 2 (4.3) | 0.046 |
Underlying diseases | |||||
Diabetes mellitus | 393 (12.0) | 331 (12.3) | 59 (11.2) | 3 (6.2) | 0.359 |
Chronic obstructive pulmonary disease | 168 (5.1) | 137 (5.1) | 22 (4.2) | 9 (18.8) | <0.001 |
Abnormal liver function | 190 (5.8) | 171 (6.3) | 8 (1.5) | 11 (22.9) | <0.001 |
Hepatitis | 112 (3.4) | 90 (3.3) | 19 (3.6) | 3 (6.2) | 0.532 |
Malignancy | 25 (0.8) | 24 (0.9) | 1 (0.2) | 0 (0.0) | 0.198 |
Hypertension | 172 (5.3) | 145 (5.4) | 22 (4.2) | 5 (10.4) | 0.142 |
4 or more previous hospitalization for TB | 175 (5.4) | 135 (5.0) | 36 (6.8) | 4 (8.3) | 0.157 |
4 or more years of TB disease | 1720 (52.6) | 1272 (47.2) | 406 (76.9) | 42 (87.5) | <0.001 |
TB = tuberculosis;
MDR = multidrug-resistant;
XDR = extensively drug-resistant.