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. 2011 Apr 29;6(4):e19399. doi: 10.1371/journal.pone.0019399

Table 2. Clinical characteristics of hospitalized TB patients in the 309 Hospital.

Characteristics Total Patients with non-MDR -TB Patients with MDR-TB excluding XDR-TB Patients with XDR-TB P
n = 3270(%) n = 2694 (%) n = 528 (%) n = 48 (%)
Sites of TB 0.013
Extrapulmonary TB 256 (7.8) 228 (8.5) 25 (4.7) 3 (6.2)
Pulmonary TB 3014 (92.2) 2466 (91.5) 503 (95.3) 45 (93.8)
Lower lung field TB (n = 3024) 1575 (52.1) 1286 (52.0) 262 (52.0) 27 (60.0) 0.563
TB history <0.001
New 1392 (42.6) 1211 (45.0) 166 (31.4) 15 (31.2)
Retreatment 1878 (57.4) 1483 (55.0) 362 (68.6) 33 (68.8)
Smear-positivity at treatment onset (n = 2674) 1951 (73.0) 1526 (70.9) 392 (82.2) 33 (75.0) <0.001
Radiological findings at onset 0.545
Non-cavitary 1492 (45.6) 1239 (46.0) 234 (44.3) 19 (39.6)
Cavitary disease 1778 (54.4) 1455 (54.0) 294 (55.7) 29 (60.4)
Family history of TB, yes (n = 3205) 133 (4.1) 100 (3.8) 31(6.2) 2 (4.3) 0.046
Underlying diseases
Diabetes mellitus 393 (12.0) 331 (12.3) 59 (11.2) 3 (6.2) 0.359
Chronic obstructive pulmonary disease 168 (5.1) 137 (5.1) 22 (4.2) 9 (18.8) <0.001
Abnormal liver function 190 (5.8) 171 (6.3) 8 (1.5) 11 (22.9) <0.001
Hepatitis 112 (3.4) 90 (3.3) 19 (3.6) 3 (6.2) 0.532
Malignancy 25 (0.8) 24 (0.9) 1 (0.2) 0 (0.0) 0.198
Hypertension 172 (5.3) 145 (5.4) 22 (4.2) 5 (10.4) 0.142
4 or more previous hospitalization for TB 175 (5.4) 135 (5.0) 36 (6.8) 4 (8.3) 0.157
4 or more years of TB disease 1720 (52.6) 1272 (47.2) 406 (76.9) 42 (87.5) <0.001

TB = tuberculosis;

MDR = multidrug-resistant;

XDR = extensively drug-resistant.