Table 2. Ten SNPs used to calculate the psoriasis genetic risk score in case-control samples.

Chr	Gene	SNP	Allelesrisk/nonrisk	Risk alleles frequency		OR*	95% CI*	P-add*
				Case	Control
1	IL23R	rs11209026	G/A	0.961	0.938	1.61	1.16–2.24	0.0044
1	LCE3C/3D	rs4112788	C/T	0.701	0.635	1.37	1.18–1.58	2.31E-05
5	IL13	rs20541	C/T	0.813	0.806	1.06	0.89–1.25	0.5228
5	TNIP1/ANXA6	rs17728338	A/G	0.109	0.061	1.94	1.54–2.45	2.96E-08
5	IL12B	rs3213094	G/A	0.853	0.784	1.59	1.33–1.91	5.80E-07
6	CDKAL1	rs6908425	C/T	0.823	0.792	1.22	1.03–1.45	0.0223
6	HLA-C	rs10484554	T/C	0.351	0.158	3.07	2.61–3.61	9.67E-42
6	TNFAIP3	rs610604	C/T	0.364	0.336	1.12	0.98–1.29	0.1083
12	IL23A/STAT2	rs2066808	T/C	0.955	0.920	1.82	1.34–2.45	0.0001
20	ZNF313	rs6125829	G/T	0.646	0.616	1.13	0.98–1.30	0.0843

*P-value and ORs were adjusted for 4 principal components and gender.

Chr: Chromosome

SNP: Single nucleotide polymorphism

OR: Odds ratio

CI: Confidence intervals

P-add: P value under additive model