Table 4. The percentage of genetic variance explained by selected SNPs.
Chr | Gene | SNP | Additive genetic variance explained* |
1 | IL23R | rs11209026 | 0.0045 |
1 | LCE3C/3D del | rs4112788 | 0.0083 |
5 | IL13 | rs20541 | 0.0002 |
5 | TNIP1/ANXA6 | rs17728338 | 0.0101 |
5 | IL12B | rs3213094 | 0.0127 |
6 | CDKAL1 | rs6908425 | 0.0023 |
6 | HLA-C | rs10484554 | 0.0666 |
6 | TNFAIP3 | rs610604 | 0.0011 |
12 | IL23A/STAT2 | rs2066808 | 0.0089 |
20 | ZNF313 | rs6125829 | 0.0013 |
*The percentage of variance explained was estimated under liability threshold model.
Totally, the selected 10 SNPs could explain11.6% of genetic variance.
SNP: Single nucleotide polymorphism.
Chr: chromosome.