Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Apr 29;6(4):e19456. doi: 10.1371/journal.pone.0019456

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Zhao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Normal fundus photograph from a 12-month-old wild-type mouse. (B) Merged photos from central and peripheral retina from a 12-month-old knockout mouse, showing both dotted and patchy deposits (arrows) and RPE mottling (arrowheads). (C) Magnified picture showing spots with sharp outline and a large patchy deposit in the mid-peripheral retina (arrow). (D) Soft drusen-like deposits with larger size and ambiguous border. (E and F) Scotopic ERG recordings at +10 dB (25 cd·s/m²) flash intensity, showing significantly decreased a- and b-wave amplitudes in Nrf2 ^−/− mice when compared to age-matched wild-type mice (n = 6 per group; *P<0.05, ** P<0.01, Student's t-test).