TABLE 3.
Multivariablea relative risks of hypertension in the highest quartile versus the lowest quartile of biomarkers, stratified by measures of adiposity.
Measures of adiposity | hsCRP | IL-6 | IL-1β | TNF-r2 | sICAM-1 | |||||
---|---|---|---|---|---|---|---|---|---|---|
White | Black | White | Black | White | Black | White | Black | White | Black | |
Body Mass Indexb | ||||||||||
< 25 | 1.28 (0.68–2.41) | 2.91 (0.995–8.52) | 1.23 (0.66–2.29) | 1.57 (0.59–4.17) | 0.70 (0.38–1.30) | 2.02 (0.78–5.24) | 1.06 (0.56–2.01) | 0.97 (0.43–2.20) | 0.89 (0.48–1.64) | 0.81 (0.30–2.17) |
25 to <30 | 1.48 (0.59–3.74) | 1.10 (0.49–2.50) | 1.03 (0.47–2.26) | 0.94 (0.44–2.00) | 1.78 (0.80–3.94) | 1.41 (0.62–3.20) | 0.89 (0.41–1.92) | 1.19 (0.56–2.54) | 1.47 (0.65–3.30) | 1.53 (0.72–3.26) |
≥ 30 | 0.40 (0.04–4.06) | 0.76 (0.29–1.98) | 2.80 (0.61–12.9) | 1.79 (0.68–4.76) | 0.59 (0.18–1.88) | 0.65 (0.28–1.50) | 0.25 (0.05–1.35) | 1.91 (0.90–4.04) | 1.86 (0.50–6.92) | 1.43 (0.71–2.86) |
P, interactionc | 0.25 | 0.88 | 0.94 | 0.60 | 0.28 | 0.48 | 0.74 | 0.65 | 0.65 | 0.42 |
Waist Circumferenced | ||||||||||
<77 cm | 1.49 (0.74–2.99) | 4.43 (1.24–15.9) | 1.10 (0.54–2.26) | 1.84 (0.65–5.16) | 0.66 (0.32–1.36) | 2.34 (0.80–6.88) | 1.15 (0.57–2.29) | 1.14 (0.45–2.85) | 0.92 (0.47–1.79) | 0.98 (0.35–2.80) |
77 to <88 cm | 1.70 (0.76–3.80) | 0.55 (0.25–1.22) | 1.52 (0.69–3.36) | 1.23 (0.58–2.61) | 1.61 (0.74–3.46) | 1.85 (0.82–4.18) | 1.21 (0.56–2.59) | 1.13 (0.55–2.34) | 1.59 (0.73–3.45) | 0.81 (0.40–1.64) |
≥ 88 cm | 0.83 (0.24–2.95) | 0.91 (0.37–2.23) | 0.81 (0.29–2.25) | 0.91 (0.36–2.27) | 0.68 (0.27–1.71) | 0.65 (0.30–1.39) | 0.56 (0.20–1.56) | 1.73 (0.87–3.43) | 0.78 (0.27–2.31) | 1.80 (0.93–3.49) |
P, interactiond | 0.14 | 0.13 | 0.94 | 0.91 | 0.74 | 0.37 | 0.76 | 0.77 | 0.77 | 0.24 |
Multivariable models adjust for smoking, alcohol intake, physical activity, and hormone replacement therapy.
Models within each category of BMI also include BMI as a continuous variable.
Interactions are tested using Wald chi-square statistics.
Models within each category of waist circumference also include waist circumference as a continuous variable.