Table 3.
Sensitivity analysis: rate of incident cancers in patients with prior malignancy: followup censored after first incident malignancy*
DMARD (n = 117) | All anti-TNF (n = 177) | |
---|---|---|
Person-years of followup | 232 | 503 |
Person-years followup per patient, median (IQR) | 1.8 (1.3–2.6) | 3.0 (1.9–3.9) |
Incident malignancies, no. | 9 | 11 |
Patients with incident malignancies, no. | 9 | 11 |
Rate of incident malignancy/1,000 person-years (95% CI) | 38.7 (17.7–73.5) | 21.9 (10.9–39.2) |
IRR (95% CI) | Referent | 0.51 (0.2–1.27) |
IRR adjusted for age and sex (95% CI) | Referent | 0.52 (0.21–1.33) |
Propensity-adjusted IRR (95% CI) | Referent | 0.47 (0.10–2.22) |
DMARD = disease-modifying antirheumatic drug; anti-TNF = anti–tumor necrosis factor; IQR = interquartile range; 95% CI = 95% confidence interval; IRR = incidence rate ratio.