Terminal Hemodynamics. Panel A shows a significant reduction in left ventricular systolic pressure (LVSP) in HF rats versus Sham, and preservation in BNP rats in comparison to HF rats. A significant improvement in dP/dtmax was seen in rats treated with BNP, in contrast to the HF group (Panel B). Finally, in Panel C, left ventricular end-diastolic pressure (LVEDP) was elevated in HF rats versus BNP rats. (* p<0.05 vs. Sham, ** p<0.01 vs. Sham, *** p<0.001 vs. Sham, † p<0.05 vs. HF)