Table 1.
Characteristics of 325 participants in the DCCT/EDIC Study at the time incident persistent microalbuminuria was diagnosed
Demographic data and medical history | |
Age (years) | 33 (10) |
Female gender | 132 (41%) |
Caucasian race | 304 (94%) |
Duration of diabetes (years) | 14 (6) |
DCCT cohort | |
Primary prevention | 140 (43%) |
Secondary prevention | 185 (57%) |
DCCT treatment assignment | |
Intensive therapy | 115 (35%) |
Conventional therapy | 210 (65%) |
Time of diagnosis of persistent microalbuminuria | |
During DCCT | 170 (52%) |
During EDIC Study | 155 (48%) |
Retinopathy | 231 (87%) |
Active smoking | 99 (32%) |
RAAS inhibitor use | 24 (7%) |
Lipid-lowering medication use | 16 (5%) |
Physical examination | |
Body mass index (kg/m2) | 26.0 (4.1) |
Systolic blood pressure (mmHg) | 122 (14) |
Diastolic blood pressure (mmHg) | 78 (9) |
Laboratory data | |
Hemoglobin A1c (%) | 9.4 (1.8) |
Albumin excretion rate (mg/24hr) | 48 (37, 76) |
Estimated GFR (mL/min/1.73 m2) | 114 (30) |
Total cholesterol (mg/dL) | 190 (38) |
HDL cholesterol (mg/dL) | 51 (13) |
Triglycerides (mg/dL) | 108 (89) |
LDL cholesterol (mg/dL) | 119 (32) |
Data are mean (standard deviation) or n (%), except for albumin excretion ratio (median, inter-quartile range). DCCT = Diabetes Control and Complications Trial; EDIC = Epidemiology of Diabetes Interventions and Complications; RAAS = renin-angiotensin-aldosterone system; GFR = glomerular filtration rate.