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. 2011 Feb;58(3):383–394. doi: 10.1111/j.1365-2559.2011.03760.x

Table 4.

SP3 and 4B5 immunoscores versus percentage (IHC)-positive cells in amplified/non-amplified tumours

ISH negative ISH positive


% positive cells in IHC % positive cells in IHC


SP3 0 1–10 11–50 51–75 76–100 Subtotal SP3 0 1–10 11–50 51–75 76–100 Subtotal
0 123 0 0 0 0 123 0 0 1 1 0 0 2

1+ 0 0 0 0 1 1 1+ 0 0 2 0 1 3

2+ 0 0 0 0 0 0 2+ 0 0 2 0 4 6

3+ 0 0 0 0 0 0 3+ 0 0 4 0 7 11

4B5 0 1–10 11–50 51–75 76–100 Subtotal 4B5 0 1–10 11–50 51–75 76–100 Subtotal

0 106 0 0 0 0 106 0 0 0 0 0 0 0

1+ 0 3 10 0 3 16 1+ 0 0 1 0 0 1

2+ 0 0 2 0 0 2 2+ 0 1 2 0 1 4

3+ 0 0 0 0 0 0 3+ 0 0 6 0 11 17

ISH, In situ hybridization.