Table 3.
Sheep mechanistic study
| MR n=4 |
Control n=5 |
|||
|---|---|---|---|---|
| Before MI | After MI | Before MI | After MI | |
| LVESV (ml) | 16.2 ± 1.9 | 28.7 ± 4.3a | 19 ± 4.7 | 27.0 ± 5.4 b |
| LVEDV (ml) | 40.6 ± 2.1 | 49.8 ± 2.9 a | 45.1 ± 8.3 | 51.9 ± 11.3 |
| EF (%) | 60.2 ± 3 | 42.6 ± 5.2 a | 57.3 ± 4 | 47.4 ± 5.3 b |
| LVEDD (cm) | 4.3±0.2 | 4.1±0.2 | 4.0±0.2 | 4.2±0.3 |
| LVESD (cm) | 3.1±0.1 | 3.1±0.3 | 3.0±0.3 | 3.1±0.2 |
| Annulus max (cm) | 3.0 ± 0.1 | 3.0 ± 0.1 | 2.9 ± 0.1 | 2.9 ± 0.1 |
| Annulus min (cm) | 2.9 ± 0.2 | 2.9 ± 0.1 | 3.0 ± 0.2 | 3.0 ± 0.1 |
| Annulus change (cm) | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.1 ± 0.1 |
| TL-Diast (cm) | 2.6 ± 0.5 | 3.0 ± 0.4 | 2.3 ± 0.3 | 2.5 ± 0.3c |
| TL-Syst (cm) | 2.1 ± 0.4 | 2.9 ± 0.4 a | 2.0 ± 0.4 | 2.1 ± 0.3c |
| TL: ED-ES | 0.6 ± 0.2 | 0.2 ± 0.1 a | 0.4 ± 0.3 | 0.5 ± 0.2c |
| TH-Diast (cm) | 1.9 ± 0.2 | 2.5 ± 0.5 | 1.8 ± 0.5 | 1.9 ± 0.6 |
| TH-Syst (cm) | 1.8 ± 0.2 | 2.4 ± 0.5 a | 1.7 ± 0.5 | 1.8 ± 0.5 |
| TH: ED-ES | 0.2 ± 0.1 | 0.1 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.2 |
a
MR group, After vs. Before MI, p<0.01
b
Control group, After vs. Before MI, p<0.01
c
MR versus Control, After MI, p<0.01
Abbreviations as in Table 2.