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. 2011 Feb 15;12(5):784–794. doi: 10.1002/cbic.201000618

Table 2.

IC50 values for 12 and oleanolic acid derivative 1 with human cancer cell lines.[a]

Cell line 12 1
KB-3-1 0.3±0.08 1.2±0.16
KB-8-5 1.2±0.12 3.1±0.29
HeLa 1.3±0.28 2.8±0.37
MCF-7 5±0.34 >10
SK-N-MC 0.8±0.1 4.9±0.6
[a]

IC50 was defined as the compound concentration that resulted in 50 % cell survival as measured by the MTT assay (see Experimental Section). Incubation time: 24 h.