Skip to main content
. Author manuscript; available in PMC: 2011 May 2.
Published in final edited form as: Carcinogenesis. 2006 Jan 12;27(7):1432–1444. doi: 10.1093/carcin/bgi345

Table VI.

Best estimates with 95% CIs (in parentheses) and –loglikelihood values for different model fits: CPS-II data (fit-RIVM8), British doctors’ data (fit-RIVM9), the grouped EPIC data for males and females and the CPS-II data (fit-RIVM10), and the grouped EPIC data for males and the British doctors’ data (fit-RIVM11)

1 2
3
4
5
CPS-II, fit-RIVM8 British doctors’ data, fit-RIVM9 EPIC males and females and CPS-II, fit-RIVM10 EPIC males and British doctors’ data, fit-RIVM11
Initiation
 μ0 (per year) 2.84·10−7 (2.45·10−7–3.28·10−7) 1.07·10−7 (7.96·10−8–1.44·10−7) 2.51·10−7 (2.24·10−7–2.77·10−7) 1.65·10−7 (1.36·10−7–1.86·10−7)
y1 (day per cigarette) y1EPIC=0.17 y1EPIC=0.21 0.20 (0.16–0.25) 0.15 (0.10–0.30)
y 2 2.89 (1.40–9.40) 9.95·104 (6.10–∞) 4.87 (2.43–20.40) 12.85 (0.89–∞)
Promotion
 ε0 (per year) 4.6·10−2 (3.8·10−2–5.4·10−2) 9.8·10−2 (7.3·10−2–0.117) 5.1·10−2 (4.4·10−2–5.7·10−2) 7.2·10−2 (5.7·10−2–9.0·10−2)
 ε1 (day per cigarette) y 1 y 1 y 1 y 1
  ε 2 1.19 (0.86–1.76) 0.16 (0–0.48) 0.96 (0.75–1.26) 0.56 (0.25–1.02)
Malignant transformation
m1 (day per cigarette) y 1 y 1 y 1 y 1
m 2 0.56 (0.39–0.74) 9.76·104 (7.93–∞) 0.70 (0.54–0.88) 6.76 (2.16–∞)
 –loglikelihood 82.39 28.73 766.55
corr = +14.81)
394.54
corr = +0.50)

Values given in italic were used as fixed input and not estimated by model fits.