Table 3.
Proteins decreased in FTLD-U dentate granule cells.
| GenBank™ accession number | Protein name | Average log2 ratio1 | Average fold change | Total peptides | ||
|---|---|---|---|---|---|---|
| Comparison 1 | Comparison 2 | Comparison 3 | ||||
| NP_997637.1 | cAMP-dependent protein kinase | −2.67 | −6.34 | 1 | 1 | |
| NP_004246.1 | Cytochrome c oxidase subunit Va | −1.69 | −3.22 | 2 | 1 | |
| NP_077718.2 | NADH–ubiquinone oxidoreductase Fe−S protein 7 | −1.59 | −3.01 | 1 | 1 | |
| NP_072045.1 | Ribosomal protein S18 | −1.50 | −2.83 | 4 | 2 | |
| NP_002796.4 | Proteasome 26S ATPase | −1.10 | −2.14 | 1 | 1 | |
| NP_000972.1 | Ribosomal protein L19 | −1.06 | −2.08 | 2 | 1 | |
| NP_996734.1 | Reticulon 1 | −1.03 | −2.04 | 3 | 2 | |
| NP_006658.1 | Progesterone receptor membrane component 1 | −0.99 | −1.99 | 4 | 2 | |
| NP_000628.2 | Glutathione reductase | −0.98 | −1.97 | 1 | 1 | |
| NP_006377.2 | DEAD box polypeptide 17 | −0.98 | −1.97 | 2 | 1 | |
| NP_003008.1 | Splicing factor, arginine/serine-rich 3 | −0.92 | −1.89 | 2 | 2 | |
| AP_000642.1 | Cytochrome c oxidase subunit II | −0.83 | −1.78 | 4 | 5 | 3 |
| NP_061820.1 | Cytochrome c | −0.82 | −1.77 | 4 | 1 | |
| NP_001013.1 | Ribosomal protein S19 | −0.79 | −1.73 | 3 | 1 | |
| NP_733936.1 | Aldehyde dehydrogenase 5A1 precursor | −0.79 | −1.72 | 4 | 1 | |
| NP_036192.1 | Dynamin 1-like protein | −0.78 | −1.71 | 1 | 2 | |
| NP_001027392.1 | Syntaxin binding protein 1 | −0.72 | −1.65 | 5 | 6 | |
| NP_004823.1 | Glutathione-S-transferase omega 1 | −0.71 | −1.64 | 1 | 1 | |
| NP 613075.1 | H2A histone family, member Y | −0.63 | −1.54 | 2 | 1 | |
1Average of protein change across all three FTLD-U/control comparisons.