Table 3.
Odds ratios and 95% confidence intervals for colorectal cancer and various active smoking exposures, males only, Roswell Park Cancer Institute, 1982–1998
| Cases (%) | Control (%) | Overall male population (n = 2,031) |
Restricted to males with no current SHS exposure (n = 448) |
|||
|---|---|---|---|---|---|---|
| Odds ratioa | 95% Confidence interval |
Odds ratioa | 95% Confidence interval |
|||
| Smoking status | ||||||
| Never smoker | 205 (30.3) | 468 (34.6) | 1.00 | Referent | 1.00 | Referent |
| Ever smoker | 472 (69.7) | 886 (65.4) | 1.22 | 1.00–1.48 | 1.99 | 1.31–3.04 |
| Amount smoked | ||||||
| Never smoker | 205 (30.3) | 468 (34.6) | 1.00 | Referent | 1.00 | Referent |
| <1 Pack/day | 81 (12.0) | 178 (13.2) | 1.06 | 0.76–1.47 | 1.63 | 0.87–3.05 |
| 1 Pack/day | 174 (25.7) | 335 (24.8) | 1.22 | 0.94–1.59 | 1.66 | 1.00–2.76 |
| >1 Pack/day | 217 (32.1) | 372 (27.5) | 1.48 | 1.15–1.90 | 2.02 | 1.22–3.36 |
| ptrend = 0.01 | ptrend = 0.01 | |||||
| Years smoked | ||||||
| Never smoker | 205 (30.3) | 468 (34.6) | 1.00 | Referent | 1.00 | Referent |
| 1–21 Years | 145 (21.4) | 291 (21.5) | 1.13 | 0.88–1.47 | 1.39 | 0.82–2.37 |
| 22–37 Years | 181 (26.8) | 298 (22.0) | 1.38 | 1.08–1.77 | 1.71 | 1.01–2.88 |
| 38 or More years | 145 (21.4) | 296 (21.9) | 1.12 | 0.86–1.44 | 2.29 | 1.32–3.98 |
| ptrend > 0.10 | ptrend = 0.01 | |||||
| Pack-years (PY) | ||||||
| Never smokers | 206 (30.4) | 469 (34.6) | 1.00 | Referent | 1.00 | Referent |
| 1–22 PY | 146 (21.6) | 296 (21.9) | 1.12 | 0.87–1.45 | 1.29 | 0.76–2.19 |
| 23–45 PY | 156 (23.0) | 301 (22.2) | 1.18 | 0.92–1.52 | 1.81 | 1.08–3.02 |
| 46 or More PY | 169 (25.0) | 288 (21.3) | 1.34 | 1.04–1.72 | 2.40 | 1.36–4.23 |
| ptrend = 0.06 | ptrend = 0.01 | |||||
| PY before age 30 | ||||||
| No PY before 30 | 214 (31.6) | 488 (36.1) | 1.00 | Referent | 1.00 | Referent |
| 1–10 PY | 137 (20.2) | 279 (20.6) | 1.12 | 0.86–1.45 | 1.82 | 1.08–3.08 |
| 11–19 PY | 154 (22.7) | 299 (22.1) | 1.17 | 0.91–1.51 | 1.47 | 0.88–2.47 |
| 20 or More PY | 172 (25.4) | 287 (21.2) | 1.37 | 1.07–1.75 | 2.55 | 1.43–4.52 |
| ptrend = 0.02 | ptrend = 0.01 | |||||
a
Adjusted for various factors changing risk>10% [(a) age, (b) sex, (c) BMI, (d) WNY residence, (e) race, (f) education, (g) income, (h) family history, (i) vegetable intake, (j) meat intake, (k) other tobacco use, (l) alcohol use, or (m) aspirin use]