Table 3.
Effects of UDA on various survival parameters measured for BALB/c mice infected with a lethal dose of SARS-CoV.
| Treatment | Live/total | Mean day of death | Hazard ratioa |
|---|---|---|---|
| PSS | 3/20 | 6.0 | – |
| UDA (20 mg/kg/day) | 6/10 | 16.0 | 2.79 (1.16–6.72) |
| UDA (10 mg/kg/day) | 9/10* | Undefined | 7.74 (2.95–20.31) |
| UDA (5 mg/kg/day) | 10/10** | Undefined | 32.32 (11.39–91.76) |
| Poly IC:LC (1 mg/kg) | 10/10** | Undefined | 32.32 (11.39–91.76) |
a
Hazard ratios are relative to the PSS control.
*
p < 0.05 versus PSS control.
**
p < 0.01 versus PSS control.