Table 1.
Incidence of occult MTC in postsurgical multinodular goiter specimens
| First author (Ref.) | Year | Total no. of thyroid specimens | No. of occult MTC (%) |
|---|---|---|---|
| Atli (44) | 2006 | 815 | 3 (0.4) |
| Bertazzo (45) | 1981 | 917 | 1 (0.1) |
| Cerci (46) | 2007 | 294 | 1 (0.3) |
| Costante (47)a | 2007 | 5,817 | 15 (0.26) |
| Fernando (48) | 2009 | 32 | 1 (3.1) |
| Gandolfi (49) | 2004 | 81 | 0 (0.0) |
| Hahm (31)a | 2001 | 1,448 | 10 (0.6) |
| Niccoli (25)a | 1997 | 1,167 | 16 (1.3) |
| Pelizzo (50) | 1996 | 539 | 2 (0.3) |
| Pezzolla (51) | 2010 | 1,507 | 0 (0.0) |
| Rieu (29)a | 1995 | 469 | 1 (0.2) |
| Tezelman (52) | 2009 | 1,695b | 0 (0.0) |
| Tezelman (52) | 2009 | 1,211c | 1 (0.08) |
| Surgical total | 15,992 | 51 (0.31) |
a
Studies with routine calcitonin screening.
b
Bilateral subtotal thyroidectomy.
c
Total or near-total thyroidectomy.