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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Reg Anesth Pain Med. 2011 MAY-JUN;36(3):220–224. doi: 10.1097/AAP.0b013e3182176f5a

Figure 1. Heat anesthesia-analgesia followed by shorter latencies to heat after sciatic nerve block with ropivacaine.

Figure 1

This is an illustration of nociceptive responses of the treated (left) hindlimb to heat stimuli as a function of treatment and time (P<0.001). The last time point on the X-axis represents behavioral testing before rats were euthanized (postoperative day 12–14). The ropivacaine (RPV) group showed anesthesia at 1 hr after injection (P<0.001), compared to the vehicle group (VEH), followed by a shorter response latency to heat stimuli (†P=0.001) at 3 hr after injection. There was no evidence of transient heat hyperalgesia at 5–7 hr, or long-term heat hyperalgesia at 2 weeks.