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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Reg Anesth Pain Med. 2011 MAY-JUN;36(3):220–224. doi: 10.1097/AAP.0b013e3182176f5a

Figure 3. Mechanical anesthesia after sciatic nerve block with ropivacaine as demonstrated with Randall-Selitto testing.

Figure 3

This is an illustration of mechanical anesthesia demonstrated with Randall-Selitto testing as a function of treatment and time. The last time point (on the X-axis) represents behavioral testing before rats were euthanized (post operative day 12–14). At baseline, treatments did not significantly differ between RPV (131.9 ± 11.0 g) and VEH (126.9 ± 8.1 g) with respect to withdrawal threshold. At 1 hr after injection, the ropivacaine (RPV) group was anesthetic (249.5 ± 0.5 g) compared with VEH (176.4 ± 21.2 g) as evidenced by a higher withdrawal threshold force (P<0.001). RPV withdrawal thresholds to Randall-Selitto testing returned to baseline and did not significantly differ from VEH by 3 hr after block.