Skip to main content
. Author manuscript; available in PMC: 2011 May 2.
Published in final edited form as: J Invest Dermatol. 2010 Nov 25;131(3):688–697. doi: 10.1038/jid.2010.351

Figure 1. High Toll-like receptor 2 (TLR2) expression in rosacea skin.

Figure 1

(a) TLR and tumor necrosis factor-α (TNFα) mRNA in rosacea skin were compared with normal skin by quantitative real-time PCR (qPCR). Skin samples were obtained from the naso-malar fold of individuals with rosacea (n = 11) and compared with skin from a similar location in normal individuals (n = 8). The relative TLRs and TNF mRNA abundance against GAPDH levels were analyzed and normalized with the average of normal skin. *P<0.05. (b) Kallikrein 5 (KLK5) and TLR2 protein localization in rosacea and normal skin were visualized by immunohistofluorescence. KLK5 and TLR2 expression is colocalized and higher in rosacea skin. Scale bar = 500 μm.