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ROC curves for genome-wide enzyme identification using the ModEnzA profiles. The classification of the complete genomes of the four organisms is shown in (a). A fraction of the EC number profiles (284 out of 2075 Tier I ModEnzA profiles) were retrained with an older version of the ENZYME database and compared to PRIAM and MetaShark (b). ModEnzA-RT-Retrained ModEnzA profiles.
