Table I.
CDR sequencing and affinities of the anti-RTL1000 TCRL Fab Abs.
| Variable L chain | Variable H chain | ||||||
|---|---|---|---|---|---|---|---|
| Name | Affinity (nM) |
CDR1 | CDR2 | CDR3 | CDR1 | CDR2 | CDR3 |
| 2E4 | 33 | RASQSVSSYLA | DASNRAT | QQRSNWPPSYT | GYTFTSYYMH | IINPSGGSTSYAQKFQ | EGDNYYGDAFDI |
| 1F11 | 60 | RASQSIINSHLA | GASSRAT | QQYGTSPLT | GVSISSRSGHWG | SISYSGSTYYNPSLKS | ESHPAAALVG |
| 3A3 | 58 | RASQVISSWLA | TASSLQS | QQANSFPLT | GFTFSSYSMN | SISSSSSYIYYADSVKG | VRGHRYYYDSSGYYSSDYYYYYGMDV |
| 3H5 | 129 | RSSQSLLHSNGNNYLD | LGSNRAS | MQALQTPLT | GGSISGYYWS | YIYYSGSTNYNPSLKS | DERDAYYYGMDV |
| 2C3 | 153 | RSSQSLLHSDGNNYLD | LGSNRAS | MQALHIPLT | GFTFSSYAMH | VISYDGSNKYYADSVKG | DRSFWSGYYIINYYYYGMDV |