Table 2.

Haplotype frequencies (as to the presence of R59H and 1622–1627insG mutations and R521C and S532G polymorphisms) in patients and controls.

Haplotype	R59H;1622–1627insG; R521C;S532G*	Patients (n = 52)	Controls (n = 780)
1	1-1-1-1	0.346	0.891
2	1-2-1-1	0.365	0.003
3	1-2-1-2	0.0	0.001
4	2-1-1-1	0.058	0,001
5	2-1-1-2	0.097	0.0
6	1-1-1-2	0.019	0.068
7	1-1-2-1	0.0	0.019
8	ND	0.115	0.016

^*1 = wild-type allele; 2 = mutant allele; ND = not determined.