Figure 5.
Comparison of total DNA damage at various stages of cellular ageing measured by Comet assay. Damaged DNA was higher in senescent HDFs which was decreased with TRF treatment. aDenotes P < .05 compared to untreated young HDFs, bP < .05 compared to untreated presenescent HDFs, cP < .05 compared to untreated senescent HDFs, dP < .05 compared to TRF-treated young HDFs. Data are presented as mean ± SD, n = 6.