Table 1.

Pharmacokinetic parameters often used in DCE-MRI pharmacokinetic analysis.

Parameter	Definition	Units	Alternative names	Literature
Ktrans	Volume transfer constant between EES and blood plasma	min−1	EF, KPS	[22, 23, 26]
ve	EES volume per unit tissue volume	N/A	Interstitial space	[22, 23, 26]
vp	Blood plasma volume per unit tissue volume	N/A		[23]
kep	Rate constant from EES to blood plasma	min−1	k21	[22–26]
kpe	Rate constant from blood plasma to EES	min−1	k12	[25]
kel	Elimination rate constant	min−1		[24, 25]
Amp	Amplitude of the normalized dynamic curve	N/A	A	[24, 25]