Table 1.
ARIC Carotid MRI Study: relationship between continuous wall thickness measures and flow cytometry measures
| Flow cytometry variables | Total wall volume (n = 1,546) | Maximum segmental wall thickness (n = 1,546) |
|---|---|---|
| Platelets | ||
| GPIIb, MFI | 0.06 (0.19) | −0.03 (0.48) |
| GPIIIa, MFI | −0.03 (0.52) | −0.01 (0.84) |
| P-selectin, % | 0.02 (0.60) | 0.01 (0.74) |
| P-selectin, MFI | 0.003 (0.95) | −0.03 (0.36) |
| CD40L, % | 0.07 (0.09) | 0.04 (0.25) |
| CD40L, MFI | −0.1 (0.03) | −0.04 (0.17) |
| Monocytes | ||
| CD14, MFI | −0.14 (0.004) | −0.02 (0.62) |
| TLR-2, % | 0.11 (0.03) | 0.07 (0.04) |
| TLR-2, MFI | 0.09 (0.06) | 0.06(0.12) |
| TLR-4, % | −0.12 (0.02) | −0.01 (0.86) |
| TLR-4, MFI | −0.13 (0.007) | −0.002 (0.95) |
| PSGL-1, MFI | 0.07(0.15) | 0.01 (0.80) |
| MPO, MFI | −0.10 (0.03) | −0.05 (0.15) |
| Cellular aggregates | ||
| PMA,% | 0.06 (0.26) | 0.02 (0.59) |
Results are adjusted for age, race, gender, LDL-C, HDL-C, TG, CRP, BMI, waist/hip, diabetes, smoking, lipid-lowering therapy, and antihypertensive medications.
Standardized beta coefficients, p value in parentheses. Number of SD differences in MRI variables associated with 1 SD increment in flow cytometry measures.