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. Author manuscript; available in PMC: 2012 May 15.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Mar 21;21(10):2980–2985. doi: 10.1016/j.bmcl.2011.03.048

Scheme 2.

Scheme 2

Reagents and conditions: (a) 4-NO2-Ph-NCO, toluene, 80°C; (b) H2 (40 psi), Pd/C, EtOH; (c) aldehyde, Na(OAc)3BH, 1,2-DCE; (d) acid, BOP, Et3N, THF.