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Integrase Inhibitory Potencies of Tricyclic Hydroxy-pyrrolopyridine Triones.a
 | |||
|---|---|---|---|
| No. | n | 3′-Processing IC50 (μM) | Strand transfer IC50 (μM) |
| 4a-1 | 0 | > 111 | 10.9 ± 1.4 |
| 4b-1 | 1 | > 111 | 9.1 ± 1.1 |
| 4c-1 | 2 | > 111 | 6.0 ± 0.7 |
| 4d-1 | 3 | > 111 | 5.4 ± 0.8 |
Data was obtained from in vitro IN assays as described in reference 4.
