. Author manuscript; available in PMC: 2012 Jun 1.

Published in final edited form as: Cell Biol Toxicol. 2010 Oct 31;27(3):159–168. doi: 10.1007/s10565-010-9178-y

Table 1.

CC₅₀ values of organotin compounds against human and murine cell lines CC₅₀ (micromolars)

Cell line	Bis(Ph₂SnCl)Xylene	DPMT
EL4	5.38^a	2.41
NFS-70	3.17	1.15
Kit-225	29.85	1.5
HeLa	58.65	32.35

CC₅₀ in micromolars is defined as the concentration of compound required to disrupt the plasma membrane of 50% of cell population compared to untreated cells after 16 h of incubation. Cells with compromised plasma membrane were monitored using PI staining and flow cytometry