Table 1.
Characteristics of patients with MS and other CNS diseases
| Multiple sclerosis | Other CNS diseases | |||
|---|---|---|---|---|
| Pediatric onset (n = 43) | Adult onset (n = 50) | Children (n = 20) | Adults (n = 12) | |
| Gender: female/male (n) | 30/13 | 35/15 | 11/9 | 8/4 |
| Age at onset (years)a | 13.1/13.7 (7.9–15.9) | 34.2/35.6 (18.2–54.6) | 11.6/12.0 (6.9–15.7) | 44.6/43.7 (20.4–70.3) |
| Sample acquisition age (years)a | 14.7/14.8 (10.5–17.9) | 37.1/38.5 (20.2–58.6) | 12.3/13.1 (7.0–16.4) | 45.4/44.6 (20.4–70.8) |
| Sampling latency (years)a | 1.6/0.8 (0.0–6.6) | 3.0/1.1 (0.0–16.2) | 0.8/0.1 (0.0–7.9) | 0.9/0.5 (0.0–3.9) |
| CSF findings | ||||
| Leukocytes (cells/μL)a | 11/5 (0–75) | 11/6 (0–95) | 3/1 (0–15) | 1/1 (0–4) |
| Protein (mg/L)a | 347/338 (139–961) | 469/411 (146–992) | 325/295 (144–644) | 406/376 (203–915) |
| Intrathecal IgG synthesis (%)a | 29/24 (0–72) | 26/25 (0–80) | 2/0 (0–33) | 0/0 (0–0) |
| Oligoclonal IgG (n) | 42 | 50 | 2 | 0 |
aMean/median (range)