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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: J Alzheimers Dis. 2010;20(0 2):S591–S607. doi: 10.3233/JAD-2010-100336

Figure 4. Mild impairment of oxidative metabolism exaggerates plaque formation in plaque competent mice.

Figure 4

TD diminishes the activities of PDHC, KGDHC and transketolase, which are also diminished in AD. Just ten days of TD leads to a large exacerbation of plaque formation throughout the brain [90].