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PM2.5 exposure promotes inflammatory monocyte egress from bone marrow to blood via TLR4 pathways. Inflammatory monocyte population of TLR4wt and TLR4d mice (A) in spleen (B) in peripheral blood, (C) in bone marrow. Data are mean ± SD. (n=4–6/group; *p<0.05). Exposure duration of 20 weeks.