Table 3.
Incidence rate ratios of death at CD4 count above 350 cells/mm3 while ART näve, according to CD4 count and other patient characteristics. Results were obtained from Poisson regression models: there were 419 deaths in 80,682 person-years
| Univariable analyses | Multivariable analysis | ||||
|---|---|---|---|---|---|
| Characteristics | Risk ratio (95% CI) |
p-value | Risk ratio (95% CI) |
p-value | |
| CD4 count cells/mm3 | |||||
| 350-499 | 1 | 0.0019 | 1 | 0.0023 | |
| 500-699 | 0.75 (0.60-0.93) | 0.77 (0.61-0.95) | |||
| 700- | 0.67 (0.52-0.86) | 0.66 (0.52-0.85) | |||
| Sex | |||||
| Male | 1 | 0.78 | 1 | 0.015 | |
| Female | 1.03 (0.83-1.28) | 0.74 (0.57-0.94) | |||
| Risk group | |||||
| Homosexual men | 1 | <0.0001 | 1 | <0.0001 | |
| Heterosexual | 1.37 (1.01-1.85) | 1.83 (1.29-2.59) | |||
| IDU | 4.58 (3.63-5.78) | 5.85 (4.54-7.53) | |||
| Other / Unknown | 2.53 (1.69-3.79) | 2.97 (1.96-4.50) | |||
| Age years | |||||
| 20-29 | 1 | <0.0001 | 1 | <0.0001 | |
| 30-39 | 1.38 (1.07-1.79) | 1.41 (1.08-1.83) | |||
| 40-49 | 1.76 (1.32-2.35) | 2.09 (1.55-2.82) | |||
| 50-59 | 2.21 (1.50-3.25) | 3.24 (2.17-4.83) | |||
| Calendar year | |||||
| 1990-1994 | 1 | 0.091 | 1 | 0.035 | |
| 1995-1999 | 0.84 (0.66-1.06) | 0.71 (0.54-0.94) | |||
| 2000-2004 | 0.77 (0.61-0.98) | 0.67 (0.48-0.93) | |||
| Viral load log10 copies/ml | |||||
| −2.99 | 1 | 0.34 | 1 | 0.28 | |
| 3.00-3.99 | 0.76 (0.53-1.10) | 0.86 (0.59-1.23) | |||
| 4.00-4.99 | 1.00 (0.71-1.39) | 1.20 (0.85-1.68) | |||
| 5.00- | 0.97 (0.59-1.60) | 1.16 (0.70-1.91) | |||
| Unknown | 1.03 (0.76-1.41) | 0.96 (0.68-1.37) | |||