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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: Bioorg Med Chem Lett. 2006 May 2;16(12):3180–3183. doi: 10.1016/j.bmcl.2006.03.042

Table 1.

Antiproliferative activity of tetrahydroisoquinolines 1–4.a

Cell Line
Compound A549 HCT-116
1 0.0192 (± 0.0009) 0.0019 (± 0.0002)
2 12.9 3.87 (± 0.28)
3 4.64 (± 1.73) 0.61 (± 0.04)
4 10.1 (± 1.6) 1.40 (± 0.46)
a

Values reported are GI50 in µM.