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. Author manuscript; available in PMC: 2011 May 3.
Published in final edited form as: Ann Surg. 2011 Feb;253(2):328–335. doi: 10.1097/SLA.0b013e3181fd271c

TABLE 3.

Summary of Treatment Related Adverse Events for All Immunotherapy Treatment Cycles

All Grades N (%) Grade 3 or 4 N (%)
Local at vaccine sites
    Erythema/induration 170 (100) 0 (0)
    Pruritus 149 (88) 0 (0)
    Pain, soreness, tenderness 142 (84) 0 (0)
    Recall induration 14 (8) 0 (0)
    Blister formation 4 (2) 0 (0)
    Hyperpigmentation 1 (0.5) 0 (0)
    Skin peeling 1 (0.5) 0 (0)
Systemic
    Eosinophilia 114 (81) 2 (1)
    Flu-like symptoms/aches 31 (18) 0 (0)
    Fever 21 (12) 0 (0)
    Chills 12 (7) 0 (0)
    Fatigue 11 (6) 0 (0)
    Pruritus 9 (5) 0 (0)
    Rash 9 (5) 0 (0)
    Nausea 7 (4) 0 (0)
    Headache 5 (3) 0 (0)
    Leukocytosis 4 (2) 0 (0)
    Pruritus (not at vaccine site) 4 (2) 0 (0)
    Lymphadenopathy 3 (2) 0 (0)
    Neutrophilia 2 (1) 0 (0)
    Urticaria 2 (1) 0 (0)
    Ecchymosis 1 (0.5) 0 (0)
    Hyperglycemia 1 (0.5) 0 (0)
    Night sweats 1 (0.5) 0 (0)