Table 1.
Experiments | Groups and N | Measurement | Conditioning context | Figure |
---|---|---|---|---|
Fentanyl-induced and conditional locomotion |
Control: N = 9 Conditioned: N = 10 Unconditioned: N = 10 |
Distance (cm) Percent distance in outer zone |
Open field | 1a, 2a and b and 3 |
Cocaine-induced and conditional locomotion |
Control: N = 10 Conditioned: N = 11 Unconditioned: N = 10 |
Distance (cm) Percent distance in outer zone |
Open field | 1a and 2c and d |
Acute and conditional Straub tail to fentanyl | Control: N = 8 Conditioned: N = 8 Unconditioned: N = 8 |
Percent time that the tape is above the line |
Unheated hot plate | 1b and 4a and b |
No acute or conditional Straub tail to cocaine |
Control: N = 4 Conditioned: N = 4 Unconditioned: N = 3 |
Percent time that the tape is above the line |
Unheated hot plate | 1b and 4c and d |
Acute fentanyl analgesia | Vehicle: N = 11 Fentanyl: N = 9 |
Hot plate latency (s) | 52.5 °C hot plate | 5a |
Conditional analgesia | Control: N = 10 Conditioned: N = 19 Unconditioned: N = 14 |
Hot plate latency (s) | Train: unheated hot plate Test: 52.5 °C hot plate |
1b and 5b |
Effect of drug expectation on conditional place preference and locomotion |
Daily: N = 21 Drug: N = 19 No drug: N = 21 |
Time on fentanyl side (s); distance (cm) |
Train: drug- and vehicle-paired chambers Test: access to all 3 chambers |
1c and 6a and b |
Effect of vehicle injections on change in preference and locomotor activity |
N = 15 | Time spent on all three sides (s); distance (cm) |
Train: vehicle in both chambers. Test: access to all 3 chambers |
6c and d |